Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 9 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate (800 mcg L-methylfolate) (as L-methylfolate as Metafolin®)
1,333 mcg DFE
333%
Top Medical Research Studies
7
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More
8
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More
Most Useful Reviews
9
Reduced homocysteine levels
59 people found this helpful
This folic acid folate was a lifesaver when preparing for pregnancy with a gene mutation. It helped lower my homocysteine, ensuring a healthy pregnancy. No side effects, and everything went well; I highly recommend it!
Read More
9
Enhanced tissue healing
27 people found this helpful
The Solgar Metafolin tablets are exceptional. They began healing lifelong angular cheilitis, improved skin health, and I started dreaming well again. This product significantly improved my healing processes.
Read More
9
Improved cardiovascular health
10 people found this helpful
I took one tablet daily after meals and also took B12 and other vitamins. My homocysteine dropped from 10.6 to 5.6 after 1.5 months, greatly reducing my risk of cardiovascular diseases. My parents experienced similar improvements.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More
7
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced homocysteine levels
59 people found this helpful
This folic acid folate was a lifesaver when preparing for pregnancy with a gene mutation. It helped lower my homocysteine, ensuring a healthy pregnancy. No side effects, and everything went well; I highly recommend it!
Read More
9
Enhanced tissue healing
27 people found this helpful
The Solgar Metafolin tablets are exceptional. They began healing lifelong angular cheilitis, improved skin health, and I started dreaming well again. This product significantly improved my healing processes.
Read More
9
Improved cardiovascular health
10 people found this helpful
I took one tablet daily after meals and also took B12 and other vitamins. My homocysteine dropped from 10.6 to 5.6 after 1.5 months, greatly reducing my risk of cardiovascular diseases. My parents experienced similar improvements.
Read More
9
Cervical cells normalised
6 people found this helpful
After starting my daughter on 800 mcg of folic acid for abnormal cervical cells, her results returned to normal after further biopsies. We'll continue taking it for life. Highly recommended!
Read More
9
Improved folic acid levels
1 people found this helpful
High quality and effective. I took these as prescribed by my hematologist since I can’t absorb regular folic acid. After three months, my folic levels increased significantly. This product really works!
Read More
Frequently Asked Questions
7.5
Effective treatment noted
182 people found this helpful
A high-quality product, very effective. The doctor prescribed it, and I felt the effects from the first month.
9
Effective gene support
1 people found this helpful
For those who can't use regular folic acid due to genetic issues, methyl folate is the answer. I lowered my high homocysteine level from 8.7 to 5.6 in just two months!
9
Improved cardiovascular health
10 people found this helpful
I took one tablet daily after meals and also took B12 and other vitamins. My homocysteine dropped from 10.6 to 5.6 after 1.5 months, greatly reducing my risk of cardiovascular diseases. My parents experienced similar improvements.
9
Reduced homocysteine levels
59 people found this helpful
This folic acid folate was a lifesaver when preparing for pregnancy with a gene mutation. It helped lower my homocysteine, ensuring a healthy pregnancy. No side effects, and everything went well; I highly recommend it!
9
Enhanced tissue healing
27 people found this helpful
The Solgar Metafolin tablets are exceptional. They began healing lifelong angular cheilitis, improved skin health, and I started dreaming well again. This product significantly improved my healing processes.
9
Cervical cells normalised
6 people found this helpful
After starting my daughter on 800 mcg of folic acid for abnormal cervical cells, her results returned to normal after further biopsies. We'll continue taking it for life. Highly recommended!
7.5
Supports cellular functions
Folates are crucial for normal nervous system function, DNA and RNA synthesis, red blood cell production with vitamin B12, and lowering blood cholesterol levels.
6
Essential for health
2 people found this helpful
Folate is vital for the nervous system, DNA synthesis, and lowering cholesterol levels. It aids in the production of red blood cells with vitamin B12, critical for overall health.
8
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
7
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
References
- Garoufi A, Papadaki M, Kalogiannis M, Zerva U, Charakida M, et al. Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia. Biomolecules. 2024;14. doi:10.3390/biom14121608
- Qi J, Wu H, Chen H, Han W. Genetically predicted lipid traits mediate the association between folic acid and atherosclerosis. Sci Rep. 2024;14:19052. doi:10.1038/s41598-024-69728-2
